Medicine Boxes

From $1.25 / unit

500 units minimum · 7 days from approved proof

Medicine boxes are secondary folding cartons sized around a packaged medicine (a bottle, blister card, tube or small device) with panels planned for customer-approved labeling, including Drug Facts where applicable, plus directions, warnings and codes. Packaging Dock builds them on Reverse Tuck or Seal End cartons from approved artwork and ships them flat across the USA.

Sized to the bottle, blister, tube or device
Panels planned for customer-approved labeling, including Drug Facts where applicable
Leaflet space and inserts where required
Reverse Tuck or Seal End closure
500 units minimum · 7-day standard production

SKU PD-MEDICINEBOXES

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Medicine boxes in carton format with tamper-evident seals and barcodes, shown alongside pill bottles and a blister pack on a pharmacy counter.

Product Details

Overview & Specifications

What Are Medicine Boxes?

Medicine boxes are the printed outer cartons that hold a medicine's primary container. The bottle or blister keeps the product; the carton carries the information panels, organizes any leaflet and identifies the product on the shelf. For over-the-counter drugs sold in a carton, the Drug Facts label goes on the outside carton.

They are part of the Tuck Boxes range and Packaging Dock's Pharma Packaging.

What it has to do

What a Medicine Carton Has to Do

A medicine carton has to fit the primary container, carry the required label copy legibly, hold the leaflet, close in the way the product requires and keep each version's artwork under control. Each need below is matched to the option that meets it.

01
Fit
Fit the Primary Container
Bottles, blister cards, tubes and devices each need their own inside size. The carton is cut around the exact primary pack plus any leaflet, so the product neither rattles nor jams.
02
Carry
Carry the Required Copy Legibly
When an OTC drug is sold in a carton, the Drug Facts label goes on that carton. Panels are sized for the approved copy at a readable type size before decoration is added.
03
Hold
Hold the Leaflet or Insert
Patient leaflets and instructions need a place that does not crush the product. Leaflet space, partitions or a paperboard insert are planned with the inside size.
04
Close
Close the Way the Product Requires
A tuck end opens and recloses; a glued Seal End stays shut until opened. FDA guidance states that glued end flaps alone do not meet the OTC tamper-resistant packaging requirements, so any tamper-evident feature is specified and validated separately.
05
Keep
Keep Versions and Codes Controlled
Strengths, counts and markets each need their own approved artwork. Carton artwork is produced only from approved files, with space for lot and expiry codes where required.

Which Tuck Structure Fits a Medicine Box

Reverse Tuck and Seal End are the two carton structures used for medicine boxes. Choose by how the carton should close and how it is filled.

Structure	How It Closes	Choose When
Reverse Tuck	Tucks on opposite sides, reclosable	The carton is opened and closed during use
Seal End	Glued end panels	The carton should stay closed until first opened

Neither structure is tamper-evident on its own. For supplements see Supplement Packaging; for shipping cartons see Pharmaceutical Shipping Boxes.

Medicine Box Specifications

Medicine boxes are specified around the primary pack, the approved copy and the closure. Review the specifications below to plan the carton.

Specification	Available Configuration
Product Type	Secondary folding carton for pharmaceutical and healthcare products
Category	Tuck Boxes
Structure	Reverse Tuck or Seal End, chosen by closure and filling process
Dimensions	Customized around the bottle, blister, tube, device and any leaflet
Board	Paperboard 14–18 pt, 20–24 pt or 26–28 pt; E/F-flute or B-flute corrugated
Closure	Reverse tuck or glued seal end; tamper-evident features specified and validated separately
Interior	Leaflet space, partitions, inserts or product supports where required
Production	Material, artwork, codes and closure requirements confirmed before manufacture
Inserts	Paperboard, foam/EVA or molded pulp
Print Coverage	Exterior only, exterior + interior, or full inside and outside
Print / Finishes	CMYK and Pantone spot color from approved artwork; finishes selected for readability of required copy
Starting Price	From $1.25 / unit; final price depends on size, board, print and quantity
Minimum Order	500 units
Standard Production	7 days from approved proof
Rush Production	Available on request
Shipping	Ships flat, USA and worldwide

What Size Medicine Box Do I Need?

Size the carton from the primary pack and any leaflet, then add a fit allowance. Measure the actual bottle with its cap, or the blister card stack, rather than catalog dimensions. The Reverse Tuck sizing guide lists carton allowances.

Primary Pack	What to Record
Bottle	Diameter and height with the cap
Blister cards	Card length, width and stack height for the card count
Tube	Length, crimp width and cap diameter
Leaflet	Folded leaflet size and thickness

Check With the Filled Primary Pack

Pack a filled bottle or the full blister stack with its leaflet, then close the carton. Check fit, copy legibility and code position.

What to Check Before Bulk Production

Review a packed sample with the final primary pack, leaflet and approved artwork. Record the approved size, closure and code area on the signed-off sample.

If the sample shows	Review before approval
Required copy crowded or small	Enlarge the carton panel or move secondary copy
Leaflet crushes the product	Add leaflet space or an insert
No space for lot and expiry codes	Reserve a code area on an end or side panel
Tamper evidence needed	Specify a separate feature and validate it

Seven days covers standard production from approved proof once the specification is confirmed; delivery timing is confirmed separately.

Customization

Customize Your Medicine Boxes

Medicine boxes are customized around four choices: primary container fit, artwork and information hierarchy, closure and opening evidence, and material documentation. Start with the primary pack and the approved copy, because together they set the panel sizes.

Primary Container Fit

Provide the exact dimensions of the bottle, blister, tube or device and any leaflet or insert that must fit inside.

Artwork and Information Hierarchy

Plan panels around required copy, warnings, directions, codes and brand elements without letting decoration reduce readability.

Closure and Opening Evidence

Specify whether standard tuck access, adhesive sealing or a separate tamper-evident feature is required. The carton is not tamper-evident by default.

Material and Documentation

Confirm any material, migration, traceability or documentation requirements that apply to the actual product and market.

Ordering

How to Order Medicine Boxes

Ordering medicine boxes takes five steps: share the product and approved copy, confirm the size and dieline, approve the artwork proof, move into production, and ship flat. Orders start at 500 units, with standard production in 7 days from approved proof after the final specification is confirmed.

01
Request a Quote
Share the primary pack dimensions, any leaflet, the approved copy, closure requirement, quantity and number of versions. Packaging Dock typically responds to quote requests within 24 hours.
02
Confirm the Size and Dieline
Inside size, structure and board are developed around the primary pack. Packaging Dock then provides a custom dieline marking the labeling panels (including Drug Facts where applicable), code area and leaflet space.
03
Approve the Artwork and Proof
Artwork is prepared on the dieline from approved files. The proof is checked against the approved copy for text, panel placement and code areas before approval.
04
Production
Production begins after the artwork proof and final specification are approved. Standard production is 7 days from approved proof, with rush production available on request.
05
Shipping
Finished cartons ship flat across the USA and worldwide. Transit method, delivery time and shipping cost depend on the destination, order volume and shipment requirements.

Sample note: A pre-production sample can be packed with the filled primary pack and leaflet before the full production run.

Uses

Who Uses Medicine Boxes?

Medicine boxes are used by OTC drug brands, pharmacies, healthcare and wellness companies that need a printed secondary carton for bottled tablets, blister packs, tubes and small devices.

01
Bottled Tablets and Capsules
Secondary cartons organize bottles with leaflets or instructions where required. Plan for the bottle with its cap.
02
Blister-Pack Products
Cartons sized around one or more blister cards plus patient or product information. Plan for the stack height.
03
Topical Tubes and Small Healthcare Products
Creams, gels and related products supplied in primary tubes or containers. More formats under Pharma Packaging.
04
Small Medical or Wellness Devices
Suitable non-sterile or already protected products with instructions and identification, subject to applicable requirements.

Structures

Explore Related Pharma Packaging

Supplements and vitamins are covered on Supplement Packaging; outer shipping cartons on Pharmaceutical Shipping Boxes; child-resistant pouches on Child-Resistant Mylar Bags. All pharma formats sit under Pharma Packaging.

FAQ

Medicine Box FAQs

What are medicine boxes?

They are printed secondary folding cartons that hold a medicine's bottle, blister card, tube or device, with panels for the approved label copy.

Are medicine boxes automatically pharmaceutical-compliant?

No. Compliance depends on the product, market, materials, artwork, manufacturing controls and applicable regulations. The carton alone does not establish compliance.

Does the Drug Facts label go on the carton?

For OTC drugs sold in an outside carton or wrapper, yes. The Drug Facts label goes on the outside container; the immediate container carries it only when there is no carton.

Are the cartons tamper-evident?

Not by default. FDA guidance states glued end flaps alone do not meet the OTC tamper-resistant requirements, so a tamper-evident feature is specified and validated separately.

Can required warnings and dosage information be printed?

Yes, from customer-supplied and approved artwork, subject to print and legibility requirements.

Can the carton hold a leaflet or insert?

Yes. Internal space can be developed around leaflets, instructions, partitions or product supports where required.

Which carton structure do medicine boxes use?

Reverse Tuck for reclosable cartons or Seal End for cartons that stay glued shut until opened.

Can you make pill boxes?

Packaging Dock makes printed cartons for pill bottles and blister cards on this page, not pill organizers.

Can I get a sample before ordering?

Yes. Complimentary sample kits ship within two business days; the customer covers shipping. A pre-production sample can also be packed with your primary pack.

What is the minimum order and lead time?

Orders start at 500 units from $1.25 per unit. Standard production is 7 days from approved proof once the final specification is confirmed, with rush production available on request.